UK-EGG Steering Group
Catherine Willis (Website coordinator) is a Principal Genetic Counsellor at Wessex Regional Genetics Service. She has a degree in Biological Sciences from the University of Warwick and after graduating trained as a Nurse at St Mary’s Hospital, London. In 2000 she completed her MSc in Human Molecular Genetics with Counselling from Imperial College, London whilst working at Moorfields Eye Hospital as a Research Nurse/Genetic Counsellor in the Medical Retina Department led by Professor Alan Bird and with Professor Tony Moore in Paediatric Ophthalmology. Since 2004 she has been at Wessex Regional Genetics Service and is the lead Genetic Counsellor for Ophthalmic Genetics.
Nicola Ragge (Nicky) is a Consultant Geneticist, Birmingham Women’s Hospital, Birmingham; honorary Consultant, Dept of Ophthalmology, Queen Elizabeth Hospital, Birmingham, and Professor in Medical Genetics, Oxford Brookes University, Oxford. Nicola Ragge trained in Paediatrics before entering Ophthalmology. After her general Ophthalmology training, she undertook Fellowships in Paediatric Ophthalmology, Neuro-ophthalmology, Adnexal Surgery, Ophthalmic Genetics at centres including: UC, San Francisco, Children’s Hospital Los Angeles, Great Ormond St Hospital and Moorfields Eye Hospital, London. She started to specialise in understanding the genetics of congenital eye anomalies, mainly anophthalmia and microphthalmia in 1999 whilst working in the Adnexal Dept at Moorfields Eye Hospital with Professor Richard Collin and set up a joint multidisciplinary clinic. In 2003, she was awarded a Senior Surgical Scientist Fellowship to establish a research programme in developmental eye genetics in Oxford whilst working as Consultant Paediatric Ophthalmologist in Moorfields and Birmingham Children’s Hospital. She undertook specialist training in Clinical Genetics to become dual accredited in Genetics and Ophthalmology, and now works as a consultant geneticist, with a special interest in developmental eye genetics and runs a national laboratory research programme on Eye Genetics in Oxford. She has identified new genes and syndromes involving eye anomalies and has established new rapid diagnostic testing for these genes. She has wide-ranging research interests, has published over 80 papers, and a book ‘Immediate Eye Care’. She has worked as Associate Editor of the Journal of Medical Genetics. She is medical advisor to the Microphthalmia, Anophthalmia, Coloboma support group.
Denize Atan is an Honorary Consultant Ophthalmologist specialising in Paediatric and Adult Neuro-Ophthalmology at Bristol Eye Hospital and a Senior Lecturer at the University of Bristol. After completing her medical training at the Universities of Cambridge and Oxford, Denize went on to train in General Medicine and Ophthalmology before undertaking a Senior Clinical Fellowship in Paediatric and Adult Neuro-Ophthalmology in Birmingham, one of the largest Neuro-ophthalmology centres in the UK, with Mike Burdon, Tim Matthews, Andrew Jacks, Susie Mollan and Manoj Parulekar. Alongside her clinical training, Denize was awarded her PhD in Ocular Genetics from the University of Bristol under the tutelage of Amanda Churchill and Professor Dick with funding from the Wellcome Trust, followed by a postdoctoral Wellcome Trust Fellowship in Neurogenetics at Sick Kids Hospital in Toronto with Professor Rod McInnes. Her current research aims to investigate how genes regulate neurodevelopment, neurodegeneration and neuro-inflammation, as well as using novel methods in genetic epidemiology to determine the impact of environmental risk factors on common ocular diseases.
Dr Mariya Moosajee is a Consultant Ophthalmologist in Genetic Eye Disease at Moorfields Eye Hospital and Great Ormond Street Hospital for Children, and a Wellcome Trust Beit Prize Clinical Research Career Development Fellow and Senior Lecturer at UCL Institute of Ophthalmology. She graduated with First Class Honours in Biochemistry and Molecular Genetics BSc in 2000, Medicine (MBBS) in 2003, and was awarded her PhD in Molecular Ophthalmology in 2009 all from Imperial College London. Her current clinical focus is providing a genomic medicine service for children and adults affected with all forms of genetic eye disease including congenital eye defects and inherited retinal dystrophies. She undertakes detailed clinical studies to understand the natural history of retinal disease to identify accurate outcome measures for clinical trials. Dr Moosajee also leads her own research group at the UCL Institute of Ophthalmology and her specialist interest is understanding the molecular basis of ocular maldevelopment and inherited retinal dystrophies, using zebrafish disease models and human induced pluripotent stem cell derived retinal cells. Through dissecting the molecular and cellular pathways of disease, Dr Moosajee and her team have identified potential therapeutic targets and developed treatment strategies, including nonsense suppression therapy for inherited retinal diseases, which is translational and applicable to a wide range of genetic eye disorders.
Previous Committee Members
We should like to thank the following members for their hard work and support on the Steering Committee:
- Andrew Webster – Moorfields Eye Hospital, UCL
- Professor Tony Moore – Moorfields Eye Hospital, UCL
- Ruth Newbury-Ecob – Royal United Hospital, Bath
- David Robinson – Southampton Regional Genetics Service
- Professor Marcela Votruba – Cardiff University, University Hospital of Wales
- Simon Ramsden – Saint Mary’s Hospital, Manchester
- Georgina Hall – Manchester Centre for Genomic Medicine
- Susan Downes – Oxford Eye Hospital, Oxford University Hospitals, University of Oxford
- Professor Graeme Black – Central Manchester University Hospitals
16 years of support for ophthalmic clinicians and clinical geneticists