“A place to share knowledge on inherited eye disease and train the next generation of clinicians and scientists.”
Postdoctoral Research Associate in Molecular Neuroscience
– Cardiff University
Applications are invited for a Postdoctoral Research Associate to join Professor Marcela Votruba’s Mitochondria and Vision Research laboratory as a part of a multidisciplinary project supported by The British Medical Association Dawkins and Strutt (2023) grant entitled: “Mitochondrial transplantation for retinal ganglion cell rescue and health in mitochondrial optic neuropathies“, at the School of Vision Sciences, College of Biomedical and Life Sciences, Cardiff University. The successful applicant will work as part of multi-disciplinary group with an international reputation for studies into mitochondrial optic neuropathies and novel therapeutic interventions, ranging from preclinical and experimental to clinical trials supervised by clinician scientist Professor Votruba. Candidates with strong research experience and publication track records in cell and molecular biology are highly recommended to apply for this position.
Mitochondrial optic neuropathies (MON) affect at least 1 in 10,000 worldwide. They are characterised by the dysfunction of mitochondria due to defects in either nuclear or mitochondrial DNA. In MON, mitochondrial dysfunction drives visual dysfunction due to loss of RGCs, resulting in progressive and irreversible loss of vision, often starting in childhood and early adulthood. RGC degeneration is extremely hard to repair or regenerate. This leads to significant disability as loss of vision in childhood or early adult life leads to problems with mobility, employment, and independence.
This project is for a pilot study to test if mitochondrial transplantation by stem cell horizontal transfer leads to a meaningful and durable increase in mitochondrial activity in a mouse model of MON.
Please read the Job Description and Person Specification very carefully. To ensure that you demonstrate how you meet all the essential criteria in your Supporting Statement, you can use the criteria as headings to guide your application. Similarly, show how you meet as many of the desirable criteria as you can. It is unlikely that any one candidate will be able to cover all the desirable criteria as this is the position is inherently interdisciplinary. Please do not be put off if you can only meet a few of them, as you will have the opportunity to learn additional skills as part of the position.
The position is fully funded for one-year, full-time, fixed term, with an intended immediate start date. The start date is negotiable, if necessary, and will be mutually agreed upon after an offer is made.
Salary: £35,333 – £42,155 per annum (Grade 6)
Please note that it is not expected that we will appoint above grade 6.30.
For informal enquires please contact Professor Marcela Votruba: firstname.lastname@example.org
Cardiff University reserves the right to close this vacancy early should sufficient applications be received.
Cardiff University is committed to supporting and promoting equality and diversity and to creating an inclusive working environment. We believe this can be achieved through attracting, developing, and retaining a diverse range of staff from many different backgrounds. We therefore welcome applicants from all sections of the community regardless of sex, ethnicity, disability, sexual orientation, trans identity, relationship status, religion or belief, caring responsibilities, or age. In supporting our employees to achieve a balance between their work and their personal lives, we will also consider proposals for flexible working or job share arrangements.
Opportunities in Ophthalmic Genetics
Academic Clinical Lecturer in Ophthalmology or Psychiatry
Academic Clinical Lecturer in Ophthalmology or Psychiatry
Division/School – Bristol Medical School
Contract type – Annually Renewable
Working pattern – Full time
Salary We will mirror the successful applicants NHS pay and progression including transitional pay arrangements.
Closing date for applications 12-Jan-2020
The University of Bristol wishes to make an appointment to the successful Clinical Academic Training, Academic Clinical Lecturer (ACL) programme in Ophthalmology or Old Age Psychiatry commencing between December 2019 and March 2020. This is a competition NIHR Clinical Lecturer post in theme of Older People and Complex Health Needs.
Visual impairment is prevalent in the older population due to age-related eye diseases, such as cataract, age-related macular degeneration (AMD) and glaucoma. The intersection between visual impairment with other co-morbidities in older people, e.g. dementia and mental health, is less well-studied, but impacts on several aspects of healthcare, including quality of life, cognitive function, and even mortality. Consequently, interventions to alleviate vision loss have far-reaching impacts on the older population.
The programme will provide up to four years post-doctoral training or until CCT is obtained (allowing for a 6 month post CCT grace period) for the postdoctoral development of an ophthalmologist-in-training or psychiatrist-in-training who has recently completed a higher degree (i.e. PhD, MD), providing salary support to allow the clinician to set aside time to develop academic skills and, for example, compete for an externally funded postdoctoral training fellowship, and contribute toward clinical training and achievement of CCT in Ophthalmology or Old Age Psychiatry.
The ACL has flexibility to join established researchers working in three areas, depending on their interests in theme of Older People and Complex Health Needs:
- NIHR Cataract Research Programme (£2million) and National Cataract Audit: methodology developed in Bristol by this programme was adopted by the National Audit of Cataract Surgery and HQIP.
- UK Biobank Eye and Vision consortium: ~68 500 participants had detailed ophthalmic assessments with data on lifestyle, cognitive measures, physical and mental health also available.
- Bristol hosts the ARCADIA group (Alliance for Research into Complex And chronic Disorders of Ageing): a multi-disciplinary translational research collaboration of clinical academics and preclinical scientists in basic science, ophthalmology, dementia, neurology, nephrology, urology, psychiatry, psychology, population health, imaging, and ethics. ARCADIA has access to multiple national and international Dementia cohorts as well as the Dementia Brain Bank and Brains for Dementia Research study.
The ACL will benefit from the interdisciplinarity of these established research groups to investigate the multiple impacts of vision loss, surgical interventions in ophthalmology and visual rehabilitation in the older population.
We welcome applications from all members of our community and are particularly encouraging those from diverse groups, such as members of the LGBT+ and BAME communities, to join us.
To apply, please click HERE.
MSc Genomic Medicine – Southampton
Genomic technologies are transforming healthcare and our flexible programme will ensure you are at the forefront of this rapidly evolving field.
Our leading experts will provide you with a comprehensive perspective on genomics applied to clinical practice and medical research, with a particular emphasis on genomic testing in the UK NHS.
Introducing your course
Richard Newitt Postgraduate Taught Bursaries worth £4000 are now available- view our Fees and Funding page for details.
Southampton’s full-time or part-time MSc Genomic Medicine programme explores the genomics and informatics of rare and common diseases, cancer and infectious diseases, and the application of these for diagnostics, prognostics and stratified medicine.
Our programme is suitable for science graduates seeking to apply genomics to their future careers, and for health professionals from medicine, nursing, public health and clinical sciences.
Our flexible postgraduate course offers you the option of tailoring your learning to suit your needs and career aspirations. You can choose from studying single modules, a PG Certificate, a PG Diploma or the full MSc, and we have full-time and part-time study options.
It will equip you with the skills to improve diagnosis and personalised treatment, as well as how to disseminate this knowledge to your peers, patients and the public.
After completing my MSc in Genomic Medicine at Southampton I have increased my breadth and depth of knowledge and it helped me to realise how other disciplines are also using genomics to improve patient care.
Research, Collaboration and Recruitment Opportunities
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Academic Clinical Lecturer – Bristol
16 years of support for ophthalmic clinicians and clinical geneticists